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                      Low Iron Levels May Increase Heart Disease Risk

                      Published by Life Extension

                      BBQ steak with grilled vegetables on cutting board

                      A recent study at University College London found low iron levels may increase a person’s risk of developing heart disease.

                      Previous research has shown that iron status, the amount of iron in the body, is linked to cardiovascular disease, or CVD, risk. Researchers have struggled in the past to show a direct link and have often had conflicting results.

                      “Previous studies have suggested a link between iron levels and heart disease, but it has been difficult to pick this apart from other confounding factors,” Dr. Dipender Gill, a Wellcome Trust Clinical Fellow at Imperial College London, said in a press release.

                      The current study, published July 6 in the journal Arteriosclerosis, Thrombosis, and Vascular Biology, used genetic variations as a proxy for iron status showing that having a high iron status can reduce the risk of CVD and, conversely, low iron status can increase the risk.

                      Researchers analyzed genome data of more than 48,000 people to determine the impact of genetic variants on iron status, focusing on three points in the genome where a single letter difference in DNA, known as a single nucleotide polymorphism, or SNP, can increase or decrease a person’s iron status.

                      Researchers from UCL and Imperial College London used a method called Mendelian randomization to find if there is a direct or causal link between levels of iron and the risk of coronary artery disease, or CAD, and found people with lower iron status are at an increased risk of CAD.

                      “We have shown that having low iron status increases the risk of coronary artery disease, but this doesn’t mean correcting that resolves the increased risk,” Gill said. “What we have highlighted is a potential therapeutic target that we didn’t know about before, and one that’s easily modifiable.”

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                      Life Extensionists are people who believe in taking advantage of documented scientific therapies to help maintain optimal health and slow aging. The medical literature contains thousands of references on the use of antioxidant vitamins, weight loss supplements, and hormones that have been shown to improve the quality and quantity of life. Life Extensionists attempt to take advantage of this scientific information to enhance their chances of living longer in good health.

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                      This website is for informational and entertainment purposes only and is not a substitute for medical advice, diagnosis or treatment. FoodTrients – A Recipe for Aging Beautifully Grace O, author and creator of FoodTrients® -- a philosophy, a cookbook and a resource -- has a new cookbook dedicated to age-defying and delicious recipes, The Age Beautifully Cookbook: Easy and Exotic Longevity Secrets from Around the World, which provides one hundred-plus recipes that promote health and well-being. The recipes are built on foundations of modern scientific research and ancient knowledge of medicinal herbs and natural ingredients from around the world. Since the publication of her first anti-aging book, The Age GRACEfully Cookbook, Grace O has identified eight categories of FoodTrients benefits (Anti-inflammatory, Antioxidant, Immune Booster, Disease Prevention, Beauty, Strength, Mind, and Weight Loss) that are essential to fighting aging, which show how specific foods, herbs, and spices in the recipes help keep skin looking younger, prevent the diseases of aging, and increase energy and vitality. Grace O combines more exotic ingredients that add age-fighting benefits to familiar recipe favorites.

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