Rheumatoid Arthritis Now Thought Triggered by Obesity

Several of my patients have rheumatoid arthritis.  Most of them also have a little extra poundage than I would like them to have.  Many of them feel that it’s been their aching joints that have kept them from exercising more and so they have gained weight.  However, looking back at their records, in many cases their overweight preceded the onset of their RA by a few years.  It had always been my suspicion that, like other diseases, their obesity had somehow contributed to the development of their condition.  Now, researchers at the Mayo Clinic have backed up my suspicions.  I’d like to tell you about what they found.

Being Overweight Can Trigger Rheumatoid Arthritis

Recent research out of the Mayo Clinic has shown that the incidence of rheumatoid arthritis had risen throughout the years 1985-2007.  In addition, people – most notably women over 40 – accounted for 68% of the cases of RA and 30% of them were obese before being diagnosed.  The rates went even higher if these women were also smokers but being obese accounted for the more than half rate of increase in development of RA over the more stable rates for smoking alone.

The link between obesity and the development of RA, the researchers concluded, was the amount of inflammation caused in the body by the increased level ofcytokines – inflammatory chemicals produced from free radicals.  These inflammatory cytokines are stored in fat cells. Thus, the more stored fat you have, the more of these inflammatory cells you have.  Having a history of being overweight puts you – especially if you are a woman over 40 (men also get RA but usually later in life) – at significant risk for developing the arthritic condition.  The researchers warned that even though their findings did not show actual cause and effect between the two conditions, their findings provided one more reason to prevent/reduce obesity levels in the general population.

As I explain to my patients whom have been diagnosed with the condition, rheumatoid arthritis   is a condition where the immune system begins to attack the tissues of the joints of the shoulders, hands, knees, ankles and feet.  It causes swelling, inflammation and pain. Complications can arise in the form of heart disease, carpel tunnel syndrome, and lung disease.  RA can become a debilitating condition which can cause you to shy even further away from exercise that can then aggravate even more unwanted weight gain.  RA currently affects about 2 million Americans.

In another recent study published in Arthritis Care and Research, it had been noted that people with a history of obesity have a 1.2 times greater risk of developing rheumatoid arthritis.  The study defined obesity as having a body mass index (BMI) of 30 or greater.  This study’s findings were surprising based on the fact that the incidence of rheumatoid arthritis had been in decline over the past 40 years but had recently started to increase dramatically.

In fact, the American Medical Association has even advised physicians that, when we talk to patients about the increased health risks of obesity, we should now add to the list the risk of developing rheumatoid arthritis.

Reduce Obesity and Help Your Rheumatoid Arthritis

The results of these newer studies are enough to convince me that obesity not only adds to the risk of developing rheumatoid arthritis, but it also complicates it, making it harder to treat and live with.  Losing weight while on the typical steroid drugs prescribed for RA can be difficult as they can cause increased appetite.  The following are some things I recommend my RA patients do to help attain a normal weight and thereby help their RA condition:

  • Minimize sugar, both natural and artificial.  Too much sugar causes acidic conditions in your blood which fuels inflammation. Eliminate or greatly reduce refined sugar to “treat” status only.  Choose low sugar fruits like blackberries, apricots, blueberries, cranberries which are also high in antioxidants. Steer clear of high sugar vegetables like corn. Also, certain nightshade vegetables (tomatoes, eggplant, etc) can fuel inflammation.
  • Watch ratio of Omega-3 fats to Omega-6s.  Eat more Omega-3 fats than Omega-6’s in a 1:1 ratio – for every Omega-6 oil eat an Omega-3.  To reduce weight, limit your intake of fats in general to 20-30 grams a day. Omega-6 fats are most salad-dressing type vegetable oils like corn oil, safflower oil, etc. These produce inflammation in the body.  Omega-3 fats consist of olive oil, walnut oil, and avocado.
  • Limit red meat consumption.  Too much iron can also cause inflammation so limit red meat to once a week, 4-6 ounce serving.
  • Joint friendly exercise.  Non-impact exercise like swimming, riding a bicycle, can help you burn calories, tone and build muscle strength without causing joint pain and stress.    In fact, water aerobics, or swimming, in a heated pool can relieve pain and swelling in joints which reduces symptoms for days afterwards. 
  • Muscle/joint building exercise.  Resistance exercise with free weight,      stationary weight machines, or resistance bands not only strengthens muscles but it builds bone by causing friction which stimulates bone growth. Do exercises designed to build muscles around your knees, shoulders, ankles, hands.  Start      with light weights, 15 minutes 3 times a week and build up weight amount and time to 30 minutes, 3 times a week.       

Rheumatoid arthritis is an uncomfortable condition which has been research proven to be aggravated by, and likely contributed to by, obesity.  Reaching and keeping a normal weight can go a long way in helping prevent developing RA and/or reducing its symptoms significantly.

Stay Well,

Mark Rosenberg, M.D.

About Dr. Mark Rosenberg

Dr. Mark A. Rosenberg, MD Dr. Mark Rosenberg received his doctorate from Georgetown University School of Medicine in 1988 and has been involved with drug research since 1991. With numerous certifications in several different fields of medicine, psychology, healthy aging and fitness, Dr. Rosenberg has a wide breadth of experience in both the public and private sector with particular expertise in both the mechanism of cancer treatment failure and in treating obesity. He currently is researching new compounds to treat cancer and obesity, including receiving approval status for an investigational new drug that works with chemotherapy and a patent pending for an oral appetite suppressant. He is currently President of the Institute for Healthy Aging, Program Director of the Integrative Cancer Fellowship, and Chief Medical Officer of Rose Pharmaceuticals. His work has been published in various trade and academic journals. In addition to his many medical certifications, he also personally committed to physical fitness and is a certified physical fitness trainer.
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