A report published online in The Journal of Clinical Endocrinology & Metabolism reveals the finding of a trial conducted at Kaleida Health’s Diabetes-Endocrinology Center of Western New York of an anti-inflammatory benefit for an extract of Polygonum cuspidatum, which contains resveratrol.*
Twenty healthy participants were randomized to receive a dose providing 40 milligrams resveratrol per day or a placebo for 6 weeks. Blood samples were analyzed for indices of oxidative and inflammatory stress, in addition to other factors.
The research team found a reduction in reactive oxygen species, which are unstable molecules that provoke oxidative stress and inflammation, in participants who received resveratrol. The resveratrol group also experienced a decrease in the inflammation protein tumor necrosis factor-alpha as well as inflammation markers interleukin-6 and C-reactive protein (CRP). “These actions, demonstrated for the first time in vivo, are consistent with potential anti-atherogenic and anti-aging effects,” the authors write.
Editor’s note: It is possible that Polygonum cuspidatum has other beneficial compounds in addition to resveratrol.
* J Clin Endocrinol Metab. 2010 Jun 9.
Reduce inflammatory process in cells, tissues, and blood vessels, helping to slow aging and reduce risk of long-term disease.
Prevents and repairs oxidative damage to cells caused by free radicals.
Support the body’s resistance to infection and strengthen immune vigilance and response.
Improves mood, memory, and focus.
Reduces risk factors for common degenerative and age-related diseases.