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                      How vitamin D works against MS

                      Published by Life Extension

                      A report published on December 9, 2013 in the Proceedings of the National Academy of Sciences explains how vitamin D, long suspected to play a role in the prevention of multiple sclerosis (MS), works to protect against the disease.

                      Acting on the finding of previous research of a preventive benefit for vitamin D in a mouse model of MS, Anne R. Gocke, PhD, and her associates at Johns Hopkins University tested the effects of the bioactive form of vitamin D known as 1,25-dihyroxyvitamin D3 [1,25(OH)2D3] and found that administration of the vitamin prevented the animals from showing symptoms. They observed that immune system cells known as T helper cells, which attack myelin (the protective sheath that covers the nerves) in MS, were abundant in the animals’ bloodstreams, but few had migrated to their brains and spinal cords, which make up the central nervous system. Upon cessation of vitamin D treatment, the animals rapidly developed symptoms, showing that vitamin D temporarily halts the disease.

                      “With this research, we learned vitamin D might be working not by altering the function of damaging immune cells but by preventing their journey into the brain,” stated Dr Gocke, who is an assistant professor of neurology at the Johns Hopkins University School of Medicine. “If we are right, and we can exploit Mother Nature’s natural protective mechanism, an approach like this could be as effective as and safer than existing drugs that treat MS.”

                      “Vitamin D doesn’t seem to cause global immunosuppression,” she noted. “What’s interesting is that the T cells are primed, but they are being kept away from the places in the body where they can do the most damage.”

                      Johns Hopkins is currently conducting a trial of vitamin D in MS patients that will help determine whether supplementing with the vitamin is beneficial to humans.

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                      Life Extension
                      Life Extension
                      LIFE EXTENSION The Life Extension Health News team delivers accurate information about vitamins, nutrition and aging. Our stories rely on multiple, authoritative sources and experts. We keep our content accurate and trustworthy, by submitting it to a medical reviewer. Life Extensionists are people who believe in taking advantage of documented scientific therapies to help maintain optimal health and slow aging. The medical literature contains thousands of references on the use of antioxidant vitamins, weight loss supplements, and hormones that have been shown to improve the quality and quantity of life. Life Extensionists attempt to take advantage of this scientific information to enhance their changes of living longer in good health. This article is posted by permission of Life Extension.

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                      This website is for informational and entertainment purposes only and is not a substitute for medical advice, diagnosis or treatment. FoodTrients – A Recipe for Aging Beautifully Grace O, author and creator of FoodTrients® -- a philosophy, a cookbook and a resource -- has a new cookbook dedicated to age-defying and delicious recipes, The Age Beautifully Cookbook: Easy and Exotic Longevity Secrets from Around the World, which provides one hundred-plus recipes that promote health and well-being. The recipes are built on foundations of modern scientific research and ancient knowledge of medicinal herbs and natural ingredients from around the world. Since the publication of her first anti-aging book, The Age GRACEfully Cookbook, Grace O has identified eight categories of FoodTrients benefits (Anti-inflammatory, Antioxidant, Immune Booster, Disease Prevention, Beauty, Strength, Mind, and Weight Loss) that are essential to fighting aging, which show how specific foods, herbs, and spices in the recipes help keep skin looking younger, prevent the diseases of aging, and increase energy and vitality. Grace O combines more exotic ingredients that add age-fighting benefits to familiar recipe favorites.

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