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                      Diet Could Hold Back Aging

                      Published by Life Extension

                      Scientists in the North East may be a step closer to finding a way to slow down the aging process.

                      Newcastle University has identified that damaged protein could be one of the key aspects to premature ageing.

                      A team of experts found that the condition of key proteins in the mitochondria – the “batteries” of cells – could be used to predict, and eventually treat, premature aging.

                      It was established that one way of slowing down the aging process was by restricting diet to reduce the number of calories consumed.

                      A study with mice identified that by using calorie restriction, a system where the cells are deprived of nutrients, rodents were able to live longer than normal.

                      Thomas Von Zglinicki, professor of cellular gerontology at the Institute for Aging and Health at Newcastle University, said it was an important breakthrough as the study suggested differences in lifespan.

                      He said: “Free radicals have long been linked with the ageing process. Mitochondria generate the energy required to keep our bodies going but they also generate free radicals. How exactly they are involved in ageing is still controversial. Our data shows that quite minor differences can explain large variations in healthy lifespan.

                      “Essentially, what we have found is that the aging process goes slower than normal in mice that managed to form mitochondrial protein complexes more efficiently, and that we actually could help them to do so.”

                      In a complex state, proteins work together more effectively, while on their own they generate toxic free radicals which, in turn, cause cells to age more rapidly.

                      If a similar mechanism is found in people it could lead to treatments, such as new drugs to improve protein assembly.

                      Further research showed that assembly of the protein complex was the key.

                      If individual components were more scarce, the protein complex was perfect, but became more sloppy if more material was around. This then led to less efficient energy production and more release of oxygen free radicals–toxic by-products of mitochondrial metabolism.

                      Dr Satomi Miwa, joint lead researcher on the team and a specialist on mitochondrial function, said: “These data go a long way to explain how calorie restriction can improve mitochondrial function, extend lifespan and reduce or postpone many age-associated diseases.”

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                      Life Extension
                      Life Extension
                      LIFE EXTENSION The Life Extension Health News team delivers accurate information about vitamins, nutrition and aging. Our stories rely on multiple, authoritative sources and experts. We keep our content accurate and trustworthy, by submitting it to a medical reviewer. Life Extensionists are people who believe in taking advantage of documented scientific therapies to help maintain optimal health and slow aging. The medical literature contains thousands of references on the use of antioxidant vitamins, weight loss supplements, and hormones that have been shown to improve the quality and quantity of life. Life Extensionists attempt to take advantage of this scientific information to enhance their changes of living longer in good health. This article is posted by permission of Life Extension.

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                      This website is for informational and entertainment purposes only and is not a substitute for medical advice, diagnosis or treatment. FoodTrients – A Recipe for Aging Beautifully Grace O, author and creator of FoodTrients® -- a philosophy, a cookbook and a resource -- has a new cookbook dedicated to age-defying and delicious recipes, The Age Beautifully Cookbook: Easy and Exotic Longevity Secrets from Around the World, which provides one hundred-plus recipes that promote health and well-being. The recipes are built on foundations of modern scientific research and ancient knowledge of medicinal herbs and natural ingredients from around the world. Since the publication of her first anti-aging book, The Age GRACEfully Cookbook, Grace O has identified eight categories of FoodTrients benefits (Anti-inflammatory, Antioxidant, Immune Booster, Disease Prevention, Beauty, Strength, Mind, and Weight Loss) that are essential to fighting aging, which show how specific foods, herbs, and spices in the recipes help keep skin looking younger, prevent the diseases of aging, and increase energy and vitality. Grace O combines more exotic ingredients that add age-fighting benefits to familiar recipe favorites.

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